atpase activity — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T36816	S-trityl-L-Cysteine	STLC	Kinesin
	S-trityl-L-Cysteine is a non-natural amino acid and an inhibitor of Eg5, also known as KSP and Kif11, a mitotic kinesin necessary for mitotic spindle formation. S-trityl-L-Cysteine inhibits the ATPase activity of Eg5 in ...		Kinesin
T17313	(+)-SJ733	SJ000557733	ATPase , Parasite
	(+)-SJ733 (SJ000557733) is a potent Na+-ATPase PfATP4 inhibitor with antimalarial activity for the study of malaria.		ATPase , Parasite
T14965	Ciliobrevin D		ATPase , Hedgehog/Smoothened
	Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibits dynein-dependent microtubule gliding and ATPase activity ...		ATPase , Hedgehog/Smoothened
T20436	DHQ	2,3-dihydroxy-quinoxalin	ATPase
	DHQ (2,3-dihydroxy-quinoxalin) is an inducer of ATPase activity that of Herpes Simplex Virus thymidine kinase.		ATPase
TQ0184	Chebulinic acid		ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad
	Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
T3432	Cinobufagin	Cinobufagine	Apoptosis , ATPase , Autophagy
	Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.		Apoptosis , ATPase , Autophagy
TN1860	Licoflavone B		ATPase , Anti-infection , Parasite
	Licoflavone B has schistosomicidal activity, it showed high S. mansoni ATPase (IC50 of 23.78 μM) and ADPase (IC50 of 31.50 μM) inhibitory activities.		ATPase , Anti-infection , Parasite
T3186	NU2058	O6-(Cyclohexylmethyl)guanine,O(6)-Cyclohexylmethylguanine	Topoisomerase , CDK
	NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.		Topoisomerase , CDK
T12359	Paprotrain	(alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile	Kinesin
	Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.		Kinesin
T6062	Brefeldin A	BFA,Ascotoxin,Cyanein,Decumbin	ATPase , Mitophagy , Antibiotic , Autophagy , HSV , CRISPR/Cas9
	Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM). Brefeldin A can induce tumor cell differentiation and apoptosis, and also possesses autophagy inhibitory activ...
T16865	SCH28080		ATPase , Proton pump
	SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent inhibitor of acid secretion in vivo with anti-ulcer activity, an...		ATPase , Proton pump
T3926	Echinatin	Retrochalcone	Free radical scavengers
	Echinatin (Retrochalcone) disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liv...		Free radical scavengers
T5425	ML367		Epigenetic Reader Domain
	ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity		Epigenetic Reader Domain
T10693	CB-6644		Others
	CB-6644 is a selective inhibitor of the RUVBL1/2 complex and blocks the ATPase activity of RUVBL1/2 (IC50: 15 nM).		Others
T9168	NSC 617145	NSC617145,NSC-617145	DNA/RNA Synthesis
	NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner.		DNA/RNA Synthesis
T0974	Novobiocin Sodium	Albamycinsodium,Cathomycin,Albamycin	Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy
	Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim...
T8901	YUM70		Apoptosis , GPR , HSP
	YUM70 is a potent and selective glucose-regulated protein 78 (GRP78) inhibitor(with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein). It induces endoplasmic reticulum (ER) stress-mediate...		Apoptosis , GPR , HSP
T15146	DNA2 inhibitor C5		Others
	DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM)...		Others
T21254	Vonoprazan Fumarate	TAK-438,TAK 438,Vonoprazan Fumurate,TAK438	Proton pump
	Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19...		Proton pump
T10616	BRM/BRG1 ATP Inhibitor-1		Epigenetic Reader Domain
	BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1/SMARCA4 ATPase activity inhibitor (IC50...		Epigenetic Reader Domain